Thermo Fisher Scientific Human CUEDC1 Synthetic Peptide
인간 CUEDC1 단백질의 카복시 말단 16개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20619의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS(pH 7.2, 0.1% BSA) 버퍼에 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human CUEDC1.
PEP-0739 can be used as a blocking peptide with polyclonal antibody PA5-20619.
Target Information
The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation.
CUE domains are present in eukaryotic proteins involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found.
CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events.
Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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