Thermo Fisher Scientific IL-18 Monoclonal Antibody (C14)
Human IL-18 단백질을 인식하는 Mouse monoclonal antibody (Clone C14). Western blot 및 IHC(P)에서 검증됨. Recombinant IL-18(aa 37–193)을 면역원으로 사용. Protein A/G 정제, PBS + 50% glycerol 보존, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–40 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C14 |
| Immunogen | Recombinant protein Interleukin 18 (amino acids 37–193 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899098 |
Target Information
The protein encoded by this gene is a proinflammatory cytokine that can induce IFN-gamma production in T cells. The combination of IL-18 and IL-12 inhibits IL-4-dependent IgE and IgG1 production while enhancing IgG2a production in B cells. IL-18 binding protein specifically interacts with IL-18 to negatively regulate its biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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