Thermo Fisher Scientific IL-18 Monoclonal Antibody (C14)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-40 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

C14

Immunogen

Recombinant protein Interleukin 18. The antigen corresponds to amino acid range 37-193 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL-18,uniProtId:Q14116-1,ncbiNodeId:9606,antigenRange:37-193,antigenLength:193,antigenImageFileName:MA5-41616_IL-18_Q14116-1_House_mouse.svg,antigenImageFileNamePDP:MA5-41616_IL-18_Q14116-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2899098

Target Information

The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.