Thermo Fisher Scientific PRMT6 Polyclonal Antibody
PRMT6 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC 및 IHC(P) 실험에 적합하며 Human과 Mouse에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PRMT6 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (IHC): 1:100–1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 325 and the C-terminus (residue 375) of Human Protein Arginine Methyltransferase 6 (PRMT6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Bovine, Dog, Horse, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Chinese hamster, Naked mole rat, and Small-eared galago
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator of several steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator.
May play a role in innate immunity against HIV-1 infection by methylating and impairing the function of HIV-1 proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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