
Thermo Fisher Scientific LEPREL1 Polyclonal Antibody
Human LEPREL1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human P3H2 (LEPREL1, UniProt ID: Q8IVL5-1, antigen range: 177–288, antigen length: 708) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2926751 |
Product Specific Information
- Gently mix before use.
- Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence:
ANPEHMEMQQ NIENYRATAG VEALQLVDRE AKPHMESYNA GVKHYEADDF EMAIRHFEQA LREYFVEDTE CRTLCEGPQR FEEYEYLGYK AGLYEAIADH YMQVLVCQHE CV
Target Information
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability, and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues.
Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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