Thermo Fisher Scientific SLC52A2 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200

Product Specifications

Product Specific Information

• Immunogen sequence: ELGSGLQVGA PGAEEEVEES SPL
• Highest antigen sequence identity to orthologs:
  • Mouse: 57%
  • Rat: 56%

Target Information

This gene encodes a membrane protein belonging to the riboflavin transporter family. Riboflavin must be obtained by intestinal absorption as it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed into coenzymes FMN and FAD, which act as intermediaries in many cellular metabolic reactions.
Paralogous members of this gene family are located on chromosomes 17 and 20. This gene shows higher expression in brain tissue than in the small intestine.
Alternative splicing results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2, an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
[provided by RefSeq, Jul 2012]

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.