Thermo Fisher Scientific HEPN1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HEPN1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642392

Product Specific Information

Immunogen sequence: GLGIAPWVDG ESELEFRRLG MQGPLEALRR RERNTQRASF SFSFLIALSP HTVDYCHSYE LFNRRWHGHV LATQRPSLFI

Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 27%.

Target Information

This gene is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes. Also to note is that this gene maps to the 3`-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.