Thermo Fisher Scientific MAP3K4 Monoclonal Antibody (X1)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Protein Sequence:
AASRPSPSGG DSVLPKSISS AHDTRGSSVP ENDRLASIAA ELQFRSLSRH SSPTEERDEP AYPRGDSSGS TRRSWELRTL ISQSKDTASK LGPIEAIQKS

Target Information

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo, and this phosphorylation affects its interaction with TBP. It contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which altered DNA conformation and higher-order complex formation inhibit preinitiation complex assembly, thereby regulating RNA polymerase II transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.