Thermo Fisher Scientific Ly-6G Monoclonal Antibody (RB6-8C5)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

-

View 2 publications 2 publications

Flow Cytometry (Flow)

Assay-dependent

View 19 publications 19 publications

Miscellaneous PubMed (Misc)

-

View 17 publications 17 publications

Product Specifications

Published species

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

RB6-8C5

Immunogen

Normal murine bone marrow cells

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10374906

Target Information

Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow. Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.