Thermo Fisher Scientific TRAIP Monoclonal Antibody (OTI1G3), TrueMAB
Human TRAIP 단백질(aa 67-313)을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 Flow cytometry에 최적화. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 연구용으로 TRAF2 매개 신호전달 및 세포사멸 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 67–313 of human TRAIP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TRAIP is a protein containing an N-terminal RING finger motif and a putative coiled-coil domain.
A similar murine protein interacts with TNFR-associated factors (TRAF1, TRAF2) and cylindromatosis.
Interaction with TRAF2 inhibits TRAF2-mediated NF-κB activation, which is required for cell activation and protection against apoptosis.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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