Thermo Fisher Scientific PI3R6 Polyclonal Antibody
PI3R6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ELISA, Immunoprecipitation에 적합합니다. Human 및 Mouse 시료에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제 제품으로 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 590–640 on human PhosphoInositide 3-kinase regulatory subunit 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
p87PIKAP (p87 PI3K adapter protein), also known as PIK3R6 (phosphoinositide-3-kinase, regulatory subunit 6), p84 or HsT41028, is a 754 amino acid cytoplasmic protein that functions as a regulatory subunit of the PI 3-kinase p110 complex.
It is expressed in heart, dendritic cells, macrophages, and neutrophils, and drives PI 3-kinase p110 activation through interaction with PDE3B, forming a scaffolding complex.
The gene encoding p87PIKAP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes more than 1,200 genes. Notably, tumor suppressor genes p53 and BRCA1 are located on this chromosome, both playing crucial roles in DNA repair and cancer predisposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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