Thermo Fisher Scientific PRPK Monoclonal Antibody (OTI5G7)
PRPK 단백질을 인식하는 마우스 단일클론 항체로 Western blot 및 IHC(Paraffin) 실험에 적합. 인간 반응성, 비결합(Unconjugated) 형태, 1 mg/mL 농도로 제공. TP53RK 단백질을 면역원으로 사용하며 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G7 |
| Immunogen | Full length human recombinant protein of TP53RK produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723522 |
Target Information
Component of the EKC/KEOPS complex required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914).
The complex likely participates in transferring the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
TP53RK exhibits ATPase activity within the EKC/KEOPS complex and supports the catalytic subunit OSGEP.
It is an atypical protein kinase that phosphorylates Ser-15 of p53/TP53 protein, potentially contributing to its activation (PubMed:11546806).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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