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Thermo Fisher Scientific PRPK Monoclonal Antibody (OTI5A5)
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Thermo Fisher Scientific PRPK Monoclonal Antibody (OTI5A5)

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PRPK 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot 및 IHC(P) 실험에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 -20°C 보관 시 장기 보존 가능.

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pk
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마지막 업데이트 2025. 08. 05. 오전 05:35
Thermo Fisher Scientific MA526956 PRPK Monoclonal Antibody (OTI5A5) 100 ul pk판매 단위 pk ·
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775,200원VAT 포함 852,720원

Thermo Fisher Scientific · Thermo Fisher Scientific PRPK Monoclonal Antibody (OTI5A5)

Applications

Western Blot (WB)

  • Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 1:150

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone OTI5A5
Immunogen Full length human recombinant protein of TP53RK produced in E.coli
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity Chromatography
Storage Buffer PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2723520

Target Information

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914).
The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914).
TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP.
Atypical protein kinase that phosphorylates Ser-15 of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806). [UniProt]


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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