Thermo Fisher Scientific TRPV3 Monoclonal Antibody (N15/39), PerCP
TRPV3 단백질을 검출하기 위한 PerCP 결합 단클론 항체. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. Mouse IgG2a 유래로 Human, Mouse, Rat에 반응. 단백질 G 정제, 보존제 무첨가, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | |
| Immunocytochemistry (ICC/IF) | 1:100 | |
| Immunoprecipitation (IP) | Assay-dependent | |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N15/39 |
| Immunogen | Synthetic peptide amino acids 458–474 (cytoplasmic C-terminus) of rat TrpV3 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931910 |
Available Formats
Product Specific Information
1 µg/mL of MA5-45456 was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 70 kDa.
Target Information
TRPV3 belongs to a family of nonselective cation channels that function in various processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22°C and 40°C. The TRPV3 gene lies close to TRPV1 on chromosome 17, and the two proteins may form heteromeric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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