Thermo Fisher Scientific ADH5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ADH5, validated for Western blot. Recognizes cytoplasmic ADH5 protein involved in formaldehyde metabolism. Supplied as liquid, unconjugated form, 0.39 mg/mL concentration. Recommended storage at -20°C, avoid f...
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Applications and Tested Dilution
- Application: Western Blot (WB)
- Tested Dilution: 1:500 – 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–374 of human ADH5 (NP_000662.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914295 |
Product Specific Information
- Positive test controls: U-251MG, U-937
- Subcellular location: Cytoplasm
Target Information
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer and has little activity for ethanol oxidation but high activity for oxidation of long-chain primary alcohols and S-hydroxymethyl-glutathione. This enzyme plays a key role in formaldehyde detoxification, protecting against irritation and sensitization effects. Several non-transcribed pseudogenes related to this gene exist in the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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