Thermo Fisher Scientific POU6F1 Polyclonal Antibody
POU6F1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료 반응성, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제, PBS/40% 글리세롤 저장. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human POU6F1. Recombinant protein control fragment (Product #RP-106284) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663316 |
Product Specific Information
- Immunogen sequence: KPSASAPIPIT CSETPTVSQL VSKPHTPSLD EDGINLEEI
- Highest antigen sequence identity to orthologs: mouse 95%, rat 100%
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord.
It contains two DNA-binding domains—the POU-specific domain and the POU homeodomain—each with an HTH (helix-turn-helix) motif.
Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and can enhance Prolactin gene expression and activate Pit-1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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