Thermo Fisher Scientific BTK Monoclonal Antibody (OTI3A2), TrueMAB
BTK 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 버퍼 제공. 연구용으로 면역학 및 신호전달 연구에 적합.
- 카탈로그번호
- TA501094
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A2 |
| Immunogen | Full length human recombinant BTK protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. BTK interacts with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which play crucial roles in innate and adaptive immunity. It also interacts with MyD88, TIRAP, and IRAK but not TRAF-6, suggesting involvement in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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