Thermo Fisher Scientific VPS4A Polyclonal Antibody
Rabbit polyclonal antibody against human VPS4A protein. Validated for IHC (paraffin) at 1:100–1:200 dilution. Detects endogenous VPS4A. Purified by antigen affinity chromatography and supplied in PBS with 40% glycerol. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636313 |
Product Specific Information
This antibody detects endogenous levels of total VPS4A protein.
Target Information
The protein encoded by this gene belongs to the AAA protein family (ATPases associated with diverse cellular activities) and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified, sharing high amino acid sequence similarity with each other, as well as with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K⁺ transport defect 1) is considered a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with endosomal compartments and are involved in intracellular protein trafficking, similar to yeast Vps4. The gene encoding this paralog is located on chromosome 16, while the other resides on chromosome 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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