Thermo Fisher Scientific MYO5A Polyclonal Antibody
Rabbit polyclonal antibody targeting MYO5A protein for WB and IHC(P) applications. Recognizes residues 1782–1799 of chicken MYO5A. Suitable for rat and chicken cerebellum or brain; does not react with mouse. Supplied as liquid, 1 mg/mL, stored at 4°C o...
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to residues 1782–1799 of chicken MYO5A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2148490 |
Product Specific Information
- Recommended positive controls: rat and chicken cerebellum, rat brain
- PA1-24947 will not react with mouse
Target Information
MYO5A is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is an actin-based motor protein involved in cytoplasmic vesicle transport, spindle-pole alignment, and mRNA translocation.
The protein is abundant in melanocytes and nerve cells. Mutations in MYO5A cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3), and neuroectodermal melanolysosomal disease (Elejalde disease).
Multiple alternatively spliced transcript variants exist, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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