Thermo Fisher Scientific NPAS2 Polyclonal Antibody
인간 NPAS2 단백질을 인식하는 Rabbit Polyclonal Antibody로 면역조직화학(IHC) 및 면역세포화학(ICC/IF)에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 장기 보관 시 -20°C에서 안정적으로 유지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NPAS2. Recombinant protein control fragment (Product #RP-100745). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644762 |
Product Specific Information
Immunogen sequence:
SKPEFIVCTH SVVSYADVRV ERRQELALED PPSEALHSSA LKDKGSSLEP RQHFNTLDVG ASGLNTSHSP SASSRSSHKS SHTAMSEPTS TPTKLMAEAS TPALPRSATL PQELPVP
Antigen sequence identity:
- Mouse: 85%
- Rat: 87%
Target Information
Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors that contain a bHLH DNA-binding domain located amino-terminal to a PAS domain.
Neuronal PAS domain protein 2 (NPAS2, also designated PAS 4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily. NPAS2, which maps to chromosome 2p11.2–2q13, is expressed primarily in neurons during the first week of postnatal development.
Its expression pattern matches the development of learning and memory and the frontal association/limbic forebrain pathway. NPAS2 may regulate long-term memory maintenance and complex sensory information processing.
NPAS2 and MOP3 form a transcriptionally active heterodimer that binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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