
Thermo Fisher Scientific TYRO3 Monoclonal Antibody (OTI4C8), TrueMAB
TYRO3 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, IP에 적합. 인간 시료 반응성. 동결건조 형태로 제공되며 PBS 버퍼에 보존. 연구용으로 세포 신호전달 및 생리학적 과정 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C8 |
| Immunogen | Full length human recombinant protein of human TYRO3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to ligands such as TULP1 or GAS6.
It regulates physiological processes including cell survival, migration, and differentiation. Ligand binding induces dimerization and autophosphorylation of TYRO3, creating docking sites for downstream signaling molecules.
Activated TYRO3 participates in neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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