Thermo Fisher Scientific CCL23 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MKVSVAALSC LMLVTALGSQ ARVTKDAETE FMMSKLPLEN PVLLDMLWRR KIGPQMTLSH AAGFHATSAD CCISYTPRSI PCSLLESYFE TNSECSKPGV IFLTKKGRRF CANPSDKQVQ VCVRMLKLDT RIKTRKN

Target Information

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide.
This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils, and no activity on activated T lymphocytes. The protein also suppresses colony formation by multipotential hematopoietic progenitor cell lines and acts as a potent agonist of the chemokine (C-C motif) receptor 1.
Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.