Thermo Fisher Scientific CDH18 Monoclonal Antibody (6F7)
CDH18 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot, IHC, ELISA에 적합. 인간 시료 반응성. PBS 용액 형태로 제공되며, 보존제 무첨가. -20°C 보관, 반복 동결 해동 피함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F7 |
| Immunogen | CDH18 (NP_004925, 467–576 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DLLSHVTVGI RVLDVNDNPP ELAREYDIIV CENSKPGQVI HTISATDKDD FANGPRFNFF LDERLPVNPN FTLKDNEDNT ASILTRRRRF SRTVQDVYYL PIMISDGGIP
Target Information
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner, contributing to the sorting of heterogeneous cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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