Thermo Fisher Scientific CDH4 Monoclonal Antibody (2E2)
CDH4 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 ELISA에 적합. 인간 시료 반응성, 비결합형 액상 형태. Affinity chromatography로 정제되었으며 PBS buffer에 보존. 신경 및 근육 발달 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E2 |
| Immunogen | CDH4 (NP_001785, aa 635–734) partial recombinant protein with GST tag (GST alone MW 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AADADVDPNI GPYVFELPFV PAAVRKNWTI TRLNGDYAQL SLRILYLEAG MYDVPIIVTD SGNPPLSNTS IIKVKVCPCD DNGDCTTIGA VAAAGLGTGA
Target Information
CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. It also has roles in kidney and muscle development. Studies have shown stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines, providing evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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