Thermo Fisher Scientific RyR1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human RyR1 for WB, IHC, and ICC applications. Recognizes intracellular RyR1 peptide (aa 1371–1386). Lyophilized form, 0.8 mg/mL concentration. Suitable for Ca2+ signaling research in muscle and non-muscle cells.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 1371–1386 of human RyR1 (Intracellular, N-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857308 |
Product Specific Information
- Reconstitute antibody with 50 µL of double distilled water (DDW).
- Store reconstituted solution at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C. Avoid repeated freeze-thaw cycles.
- Centrifuge antibody preparations before use (10000 × g, 5 min).
- Peptide sequence: (C)RAENEKDATTEKNKKR
- Homology: Rat and mouse amino acid residues are identical.
Target Information
Ryanodine receptors (RyR1) are critical in intracellular Ca²⁺ signaling during cell activation in muscle and non-muscle cells.
The ~500 kDa receptor is found in various cell types, including lymphocytes, macrophages, granulocytes, fibroblasts, epithelial and endothelial cells, skeletal and cardiac muscle, and brain tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-111900_RyR1_P21817-1_Rabbit.svg, PA5-111900_RyR1_P21817-1_Rabbit_PDP.jpeg)
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