Thermo Fisher Scientific PDLIM3 Polyclonal Antibody
Thermo Fisher Scientific의 PDLIM3 Polyclonal Antibody는 Mouse 시료에 반응하며 Western Blot과 ELISA에 적합합니다. Rabbit IgG 기반의 비결합형 액상 항체로, 세포골격 관련 단백질 연구에 유용합니다. -20°C 보관, Affinity Chromatography로 정제됨.
- 카탈로그번호
- PA592915
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 70–230 of human PDLIM3 (NP_0011075791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806544 |
Product Specific Information
- Immunogen sequence:
KAAAHQLCLK IDRGETHLWS PQVSEDGKAH PFKINLESEP QEFKPIGTAH NRRAQPFVAA ANIDDKRQVV SASYNSPIGL YSTSNIQDAL HGQLRGLIPS SPQNEPTASV PPESDVYRML HDNRNEPTQP RQSGSFRVLQ GMVDDGSDDR PAGTRSVRAP V - Positive Samples: Mouse lung
- Cellular Location: Cytoplasm, Z line, myofibril, sarcomere
Target Information
The protein encoded by this gene contains a PDZ domain and a LIM domain, suggesting involvement in cytoskeletal assembly. It binds spectrin-like repeats of alpha-actinin-2 and colocalizes with alpha-actinin-2 at the Z lines of skeletal muscle. Located near a region of chromosome 4 implicated in facioscapulohumeral muscular dystrophy, but not directly involved in the disease. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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