Thermo Fisher Scientific PDLIM3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_0011075791) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDLIM3,uniProtId:Q53GG5-1,ncbiNodeId:9606,antigenRange:70-230,antigenLength:364,antigenImageFileName:PA5-92915_PDLIM3_Q53GG5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92915_PDLIM3_Q53GG5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.38 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806544

Product Specific Information

Immunogen sequence: KAAAHQLCLK IDRGETHLWS PQVSEDGKAH PFKINLESEP QEFKPIGTAH NRRAQPFVAA ANIDDKRQVV SASYNSPIGL YSTSNIQDAL HGQLRGLIPS SPQNEPTASV PPESDVYRML HDNRNEPTQP RQSGSFRVLQ GMVDDGSDDR PAGTRSVRAP V; Positive Samples: Mouse lung; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere

Target Information

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.