Thermo Fisher Scientific NF2 Monoclonal Antibody (AF1G4)
NF2 단백질(Merlin)을 인식하는 Thermo Fisher Scientific의 AF1G4 단클론 항체로, Western blot 및 ELISA에 사용 가능. 293T 세포를 양성 대조군으로 권장하며, 연구용으로만 사용. -20°C 보관, 액상 형태로 제공.
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Thermo Fisher Scientific NF2 Monoclonal Antibody (AF1G4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AF1G4 |
| Immunogen | Recombinant human protein purified from E.coli (His-Merlin) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2538720 |
Product Specific Information
A suggested positive control for this product is 293T cells.
Target Information
NF2 encodes a protein, Merlin, that is similar to members of the ERM family of proteins, which link cytoskeletal components with membrane proteins. Merlin interacts with cell-surface proteins, cytoskeletal regulators, and ion transport proteins.
This gene is highly expressed during embryonic development and in adults is found in Schwann cells, meningeal cells, lens, and nerve.
Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and several minor isoforms are produced by alternative splicing.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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