Thermo Fisher Scientific PON2 Monoclonal Antibody (AF3E6)
PON2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 면역침전(IP)에 적합합니다. HepG2 세포를 양성 대조군으로 권장하며, 세포 산화 스트레스 연구 및 항산화 관련 단백질 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AF3E6 |
| Immunogen | Recombinant human protein purified from E. coli (His-PON2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2538719 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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