Thermo Fisher Scientific SLC22A17 Monoclonal Antibody (OTI2D6), TrueMAB
SLC22A17 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot과 IHC(Paraffin)에 적합. Human 반응성, Affinity Chromatography 정제, PBS/BSA/Glycerol buffer 구성. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 241–300 of human SLC22A17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. They typically contain 12 predicted alpha-helical transmembrane domains and a large extracellular loop between TMDs 1 and 2. Members of the SLC22 family function as uniporters, anion exchangers, or Na(+)/l-carnitine cotransporters, and participate in absorption and excretion of drugs, xenobiotics, and endogenous compounds in various organs. They also play homeostatic roles in brain and heart. Mutations in this family can cause diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may affect drug absorption or excretion. SLC22A17 is known as a receptor for Lipocalin 2 and shows relatively high expression in hematopoietic stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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