Thermo Fisher Scientific UHRF2 Monoclonal Antibody (OTI4E10), TrueMAB
UHRF2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot에 최적화되어 있습니다. Human 종에 반응하며, 고순도 친화 크로마토그래피 정제 제품입니다. 세포 주기 조절 및 종양 형성 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–288 of human UHRF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a nuclear protein involved in cell-cycle regulation. The encoded protein acts as a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. It contains NIRF_N, PHD finger, SRA, and RING finger domains, several of which are essential for regulating cell proliferation. The protein may also contribute to intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants, some non-protein coding.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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