Thermo Fisher Scientific CDH11 Polyclonal Antibody
Thermo Fisher Scientific의 CDH11 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 Rabbit IgG 항체로, WB, ICC/IF, ELISA에 사용됩니다. 세포막 단백질 CDH11을 검출하며, 골 발달 및 침습성 종양 연구에 적합합니다. 액상 형태로 -20°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDH11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 120–400 of human CDH11 (NP_0017882) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804882 |
Product Specific Information
- Positive Samples: U-87MG, A-549, HT-29
- Cellular Location: Cell membrane, Single-pass type I membrane protein
Immunogen Sequence:
ERAQYTLMAQ AVDRDTNRPL EPPSEFIVKV QDINDNPPEF LHETYHANVP ERSNVGTSVI QVTASDADDP TYGNSAKLVY SILEGQPYFS VEAQTGIIRT ALPNMDREAK EEYHVVIQAK DMGGHMGGLS GTTKVTITLT DVNDNPPKFP QSVYQMSVSE AAVPGEEVGR VKAKDPDIGE NGLVTYNIVD GDGMESFEIT TDYETQEGVI KLKKPVDFET KRAYSLKVEA ANVHIDPKFI SNGPFKDTVT VKISVEDADE PPMFLAPSYI HEVQENAAAG T
Target Information
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
All cadherins are single-pass transmembrane proteins with a variable number of extracellular cadherin (EC) domains.
Classical cadherins contain five large N-terminal EC domains, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
Type II cadherins include human cadherin-5, -6, -8, -11, and -12, defined by the lack of a HAV cell adhesion recognition sequence.
Cadherin-11 (OB-Cadherin) is a marker of mesenchymal cells and is strongly expressed in brain, spinal cord, bone marrow, and bone cells.
It plays a role in bone development and maintenance.
Cadherin-11 is also associated with invasive breast cancer cell lines, suggesting its potential as a marker for aggressive tumor subsets.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.