Thermo Fisher Scientific Ezrin/p81 Monoclonal Antibody (CPTC-Ezrin-1)
Human Ezrin 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, Peptide Array 등 다양한 응용에 적합. Recombinant full-length Ezrin을 면역원으로 사용. Protein A/G로 정제된 액상형 항체이며, -20°C 이하에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPTC-Ezrin-1 |
| Immunogen | Recombinant human full-length Ezrin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, it serves as an intermediate between the plasma membrane and the actin cytoskeleton.
This protein plays a key role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers.
A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 7430-MSM1-P1ABX_Ezrin_P15311-1_House_mouse.svg, 7430-MSM1-P1ABX_Ezrin_P15311-1_House_mouse_PDP.jpeg)
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