Thermo Fisher Scientific Ezrin/p81 Monoclonal Antibody (CPTC-Ezrin-1)
Ezrin 단백질을 인식하는 마우스 단클론 항체로 인간 시료에 반응합니다. Western blot, IHC, Peptide Array 등 다양한 응용에 적합합니다. 비결합형 액상 형태이며 4°C에서 보관합니다. 세포막-세포골격 연결 연구에 활용됩니다.
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Applications
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPTC-Ezrin-1 |
| Immunogen | Recombinant human full-length Ezrin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers.
A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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