Thermo Fisher Scientific Human TCTN2 Synthetic Peptide
Human TCTN2 단백질의 C-말단 15개 아미노산 서열 기반 합성 펩타이드. PA5-20984 항체의 블로킹 펩타이드로 사용 가능. Assay 의존적 희석 조건. PBS(pH 7.2) 버퍼에 0.1% BSA 포함, -20°C 보관.
- 판매단위
- pk
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human TCTN2.
PEP-1098 can be used as a blocking peptide with polyclonal antibody PA5-20984.
Target Information
TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate Hedgehog (Hh)-mediated patterning of the neural tube.
While the expression pattern and function of TCTN2 is not known, it shares 49% similarity with TCTN1.
TCTN1 is expressed during embryonic development in regions participating in Hh signaling, beginning in the gastrulation stages in the ventral node.
Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating TCTN1 acts as an Hh activator.
At later developmental stages, TCTN1 is also thought to act as a repressor on the Hh pathway in the anterior and posterior neural tube.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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