Thermo Fisher Scientific MCT4 Polyclonal Antibody
Thermo Fisher Scientific의 MCT4 Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 다양한 면역분석(WB, IHC, ICC, ELISA)에 사용 가능. KLH 결합 합성 펩타이드(aa 401-465)를 항원으로 제작된 Rabbit IgG 항체로, 고순도 Protein A 정제 및 안정적 액상 형태 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MCT4, amino acids 401–465 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, designated as solute carrier family-16. Each MCT exhibits distinct substrate and inhibitor specificities and transport kinetics, reflecting the metabolic needs of the tissues where they are expressed. The MCTs, including MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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