Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Calcitonin Receptor를 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 시료에서 검출. 합성 펩타이드 면역원 기반, 액상 형태로 제공되며 4°C 또는 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from sequence of rat calcitonin receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2068962 |
Product Specific Information
PA1-30120 detects Calcitonin Receptor from human, mouse, and rat samples.
Target Information
The Calcitonin Receptor inhibits bone resorption and plays a role in development and morphogenesis.
Three alternatively spliced isoforms have been identified.
In addition to binding calcitonin, the receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.
Expression has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid.
ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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