ELK Biotechnology Prothrombin rabbit pAb
Prothrombin rabbit polyclonal antibody for WB, IHC, IF, and ELISA applications. Targets human Prothrombin (F2) involved in blood coagulation. High specificity and stability with long-term storage at -20°C.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Prothrombin rabbit pAb
제품명
Prothrombin rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | F2; Prothrombin; Coagulation factor II |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human Prothrombin (AA range 420–470) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kD |
| GeneID (Human) | 2147 |
| Human Swiss-Prot No | P00734 |
| Cellular Localization | Secreted, extracellular space |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
Coagulation factor II (Prothrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade, which ultimately results in the stemming of blood loss. F2 also contributes to maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein exhibit antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 can lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. (RefSeq, Aug 2015)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.