ELK Biotechnology NVL rabbit pAb
NVL 단백질을 인식하는 고품질 rabbit polyclonal antibody. Western blot과 ELISA에 적합하며, 인간·마우스·랫트 반응성. 핵 내 리보솜 생합성 관련 단백질 연구에 유용. -20°C에서 1년 안정 저장.
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ELK Biotechnology NVL rabbit pAb
제품 개요
NVL rabbit pAb는 NVL 단백질을 특이적으로 인식하는 rabbit polyclonal antibody로, 핵 내 리보솜 생합성 과정과 관련된 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NVL rabbit pAb |
| Alternative Names | NVL; Nuclear valosin-containing protein-like; NVLp; Nuclear VCP-like protein |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from NVL (AA range: 320-400) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 95 kD |
| Gene ID (Human) | 4931 |
| Human Swiss-Prot No. | O15381 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Isoform 2: Nucleus, nucleoplasm Isoform 1: Nucleus, nucleolus Expressed predominantly in the nucleolus; associates with pre-ribosomal particles in the nucleus. |
Background
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus.
The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.
[provided by RefSeq, Aug 2011]
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