ELK Biotechnology TMPRSS3 rabbit pAb
TMPRSS3 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 시료 반응성. 합성 펩타이드 항원으로 제작되었으며, 내이 발달 및 종양 관련 연구에 적합. -20°C에서 1년 보관 가능.
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TMPRSS3 rabbit pAb
제품 개요
TMPRSS3 단백질을 인식하는 토끼 다클론 항체입니다. 인간 및 생쥐 시료에서 반응하며, Western blot, Immunohistochemistry, Immunofluorescence, ELISA 등 다양한 실험에 사용 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | TMPRSS3 rabbit pAb |
| Alternative Names | TMPRSS3; ECHOS1; TADG12; Transmembrane protease serine 3; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human TMPRSS3 (AA range: 405–454) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 49 kDa |
| Gene ID (Human) | 64699 |
| Human Swiss-Prot No. | P57727 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are involved in various biological processes, and their malfunction can lead to human diseases and disorders. TMPRSS3 is associated with congenital and childhood-onset autosomal recessive deafness and is expressed in fetal cochlea and other tissues, playing a role in inner ear development and maintenance. It is also identified as a tumor-associated gene overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. (RefSeq, Jan 2012)
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