ELK Biotechnology ALDH3A1 rabbit pAb
ALDH3A1 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot과 ELISA에 적합합니다. 인간 및 랫트 시료에서 반응하며, 세포질 내 ALDH3A1 단백질 검출에 사용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
ALDH3A1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ALDH3A1; ALDH3; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ALDH3A1 (AA range: 236–285) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| Gene ID (Human) | 218 |
| Human Swiss-Prot No. | P30838 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Rat |
Background
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. (provided by RefSeq, Sep 2008)
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