Thermo Fisher Scientific MTERFD2 Polyclonal Antibody
Human MTERFD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MTERFD2. Recombinant protein control fragment (Product #RP-102233). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644249 |
Product Specific Information
Immunogen sequence:
ARQTPHLGEQ RRTTASLLRK LTTASNGGVI EELSCVRSNN YVQEPECRRN LVQCLLEKQG TPVVQGSLEL ERVMSSLLDM GFSNAHINEL LSVRRGASLQ QLLDIISEFI LLGLNPEPVC C VVLKKSPQLL
Highest antigen sequence identity to the following orthologs:
- Mouse: 54%
- Rat: 55%
Target Information
Members of the mTERF (mitochondrial transcription termination factor) family are mitochondrial proteins believed to function as transcription termination factors.
MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung, liver, and kidney.
It may play a role in organ differentiation during embryogenesis.
A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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