Thermo Fisher Scientific SCP2 Polyclonal Antibody
Human SCP2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 지질 대사 관련 연구용으로 적합.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCP2. Recombinant protein control fragment (Product #RP-94061) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647024 |
Product Specific Information
Immunogen sequence:
ATGLAQCAEL CWQLRGEAGK RQVPGAKVAL QHNLGIGGAV VVTLYKMGFP EAASSFRTHQ IEAVPTSSAS DGFKANLVFK EIEKKLEEEG EQFVKKI
- Highest antigen sequence identity to orthologs:
- Mouse: 94%
- Rat: 92%
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
- The proximal promoter encodes the longer SCPx protein.
- The distal promoter encodes the shorter SCP2 protein.
Both share a common C-terminus.
SCPx functions as a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, while SCP2 acts as an intracellular lipid transfer protein.
This gene is highly expressed in lipid metabolism organs and may be implicated in Zellweger syndrome, where peroxisomal deficiency impairs bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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