Thermo Fisher Scientific SALF Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Publications: [References not provided]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000
• Publications: [References not provided]

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, Raji
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of:

• N-terminal proline-rich domain
• Central region of homology specific to human stoned B-like proteins
• C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes

Co-transcription of this gene and the neighboring downstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.