Thermo Fisher Scientific PA1 Polyclonal Antibody
Thermo Fisher Scientific의 PA1 Polyclonal Antibody는 인간 PTIP-associated 1 단백질(1-50 residue)을 면역원으로 제작된 Rabbit IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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- A301978Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PA1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human PTIP-associated 1 protein (PAGR1, UniProt ID: Q9BTK6-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been found to co-regulate transcription initiated by other transcription factors.
GAS is a glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, and also interacts specifically with the alpha subunit of the estrogen receptor (ERα).
RNA interference-mediated depletion of GAS in MCF7 cells leads to decreased mRNA and protein levels of ER target genes such as pS2, c-Myc, and cyclin D1, indicating its role in ER target gene regulation.
GAS also associates with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting multiple roles in transcriptional regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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