Thermo Fisher Scientific HOXD8 Monoclonal Antibody (OTI2A1), TrueMAB
Human HOXD8 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(Paraffin)에 사용 가능. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer에 보존. 연구용 전용으로 형태형성 관련 유전자 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 69–290 of human HOXD8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters—HOXA, HOXB, HOXC, and HOXD—located on different chromosomes, consisting of 9 to 11 genes arranged in tandem.
This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5′ end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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