Thermo Fisher Scientific RNF40 Polyclonal Antibody
RNF40 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체. 인간 RNF40에 반응하며 예측 반응성은 마우스, 랫, 원숭이, 소 포함.
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Thermo Fisher Scientific RNF40 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 4–311 of Human RNF40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547806 |
Product Specific Information
- Recommended positive controls: IMR32, HeLa, HeLa NE
- Predicted reactivity: Mouse (86%), Rat (86%), Rhesus Monkey (96%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The RNF40 protein contains a RING finger motif, which mediates protein-protein and protein-DNA interactions. It interacts with the tumor suppressor protein RB1. Studies suggest RNF40 may function as an E3 ubiquitin-protein ligase, facilitating ubiquitination and degradation of syntaxin 1, a key component of neurotransmitter release machinery.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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