Thermo Fisher Scientific Phospho-CD28 (Tyr218) Polyclonal Antibody
CD28 단백질의 Tyr218 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며 Western blot에 사용 가능. 높은 특이성과 재현성을 제공하며, 연구용으로만 사용됨.
- 카탈로그번호
- PA567521
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-CD28 (Tyr218) Polyclonal Antibody
Thermo Fisher Scientific Phospho-CD28 (Tyr218) Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CD28 around the phosphorylation site of Tyr218 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692004 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T-cell specific surface glycoprotein. It belongs to the immunoglobulin superfamily and is constitutively expressed on most peripheral blood T lymphocytes.
CD28 acts as a critical T-cell co-stimulatory receptor that provides the second activation signal by binding CD80 and CD86 expressed on antigen-presenting cells. It prevents T cells from entering an anergic or apoptotic state.
In murine peripheral lymphoid organs and blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+, and CD4+8+ cells, and lower on mature thymocytes.
Diseases associated with CD28 dysfunction include mycosis fungoides and Sezary’s Disease.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.