Thermo Fisher Scientific CaMKII beta Polyclonal Antibody
CaMKII beta 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며 인간, 마우스, 랫트 반응성을 가집니다. 고순도 항원 친화 크로마토그래피로 정제되어 신경 관련 연구에 유용합니다.
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Thermo Fisher Scientific CaMKII beta Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CaMKII beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.24 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792884 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%).
- Positive control: mouse brain, rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may function in long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process, known as Ca2+/CaM trapping, is thought to play a role in synaptic encoding of information.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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