Thermo Fisher Scientific ATF2 Polyclonal Antibody
ATF2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, IP에 적합. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보유. 연구용으로만 사용 가능.
- 카탈로그번호
- PA586111
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 30–80 of Human ATF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802910 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with various viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Cellular stress such as genotoxic agents, inflammatory cytokines, and UV irradiation stimulate ATF-2 activity via phosphorylation at Thr69 and Thr71 by SAPK and p38 MAPK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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