
Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (PCRP-TSC22D1-1A2)
인간 TSC22D1 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot, ICC/IF, Flow cytometry 등 다양한 응용 가능. 200 µg/mL 농도의 액상 형태로 제공되며, PBS 버퍼에 보존. 세포 성장 및 분화 조절 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-TSC22D1-1A2 |
| Immunogen | Recombinant full-length human TSC22D1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the large family of early response genes. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter. TSC22 is part of the TSC-22/Dip/Bun family and is an intracellular protein found in the cytoplasm or nucleus. It regulates cell growth, differentiation, and apoptosis, and modulates the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in both fetal and adult tissues, notably in aortic endothelial cells, and is induced by cytokines such as TGFB. TSC22 proteins are potential therapeutic targets for leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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