Thermo Fisher Scientific PRRT2 Monoclonal Antibody (CL4233)
인간 PRRT2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, IHC(Paraffin)에서 1:5,000~1:10,000 희석으로 사용 가능. Protein A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 보관 권장. 신경계 질환 관련 연구에 적합한 연구용 항체.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL4233 |
| Immunogen | Recombinant protein corresponding to Human PRRT2 (UniProt ID: Q7Z6L0-1, Range: 152–268) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2787034 |
Product Specific Information
Immunogen sequence:
PKPALQPELP TQEDPTPEIL SESVGEKQEN GAVVPLQAGD GEEGPAPEPH SPPSKKSPPA NGAPPRVLQQ LVEEDRMRRA HSGHPGSPRG SLSRHPSSQL AGPGVEGGEG TQKPRDY
Target Information
The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord during embryonic and postnatal stages. Mutations in PRRT2 are known to cause paroxysmal kinesigenic dyskinesia, characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. PRRT2 may also be involved in benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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